Home > People > Faculty > Michael S. Yu

Research Interests

• Polymer chemistry
• Synthesis and application of protein-based materials
• Bio-inspired nanostructured materials
• Biosynthesis of artificial proteins
• Biomaterials for tissue engineering
• Polymeric liquid crystals

Group Members

• Tania Chan
• Stephanie Chinnapongse
• Dawnielle Farrar
• Daniel Kim
• Shirley Leong
• Yang Li
• Patrick Stahl
• Danielle Velez

Projects

• Collagen scaffold modification
• National Federation of the Blind Teaching Outreach
• Peptde/protein-directed synthesis and assembly of nanoparticles (NP)
• Polypeptide-based piezoelectric polymer composite

Publications

Enhanced Chondrogenesis of Mesenchymal Stem Cells in Collagen Mimetic Peptide-Mediated Microenvironment
H Janice Lee, Christopher Yu, Thanissara Chansakul, Nathaniel S Hwang, Shyni Varghese, Seungju M Yu, and Jennifer H Elisseeff . Tissue Engineering Part A In press, (2008).
DOI: 10.1089/ten.tea.2007.0204

Fabrication of Polypeptide-Based Piezoelectric Composite Polymer Film
Dawnielle Farrar, James E. West, Ilene J. Busch-Vishniac, Seungju M. Yu . Scripta Materialia Vol. 59, Issue 10, Pages 1051-1054 (2008).
DOI: 10.1016/j.scriptamat.2008.07.022

Immobilization of Growth Factors on Collagen Scaffolds Mediated by Polyanionic Collagen Mimetic Pept
Allen Y. Wang, Shirley Leong, Yu-Chuan Liang, Ru Chih C. Huang, Christopher S. Chen, and S. Michael Yu. Biomacromolecules Vol. 9, Issue 10, 2929-2936 (2008).
DOI: 10.1021/bm800727z

Spatio-Temporal Modification of Collagen Scaffolds Mediated by Triple Helical Propensity
Allen Y. Wang, Catherine A. Foss, Shirley Leong, Xiao Mo, Martin G. Pomper, and Seungju M. Yu. Biomacromolecules Vol. 9, Issue 7, 1755-1763 (2008).
DOI: 10.1021/bm701378k

Directed Synthesis and Assembly of Nanoparticles Using Purple Membrane
Xiao Mo, Mark P. Krebs, Seungju M. Yu. Small Vol. 2, Issue 4, 526-529 (2006).
DOI: 10.1002/smll.200500431

Nanoparticle-Assisted Visualization of Binding Interactions between Collagen Mimetic Peptide
Xiao Mo, Yoojin An, Chang-Soo Yun, Seungju M. Yu. Angewandte Chemie International Edition Vol. 45, Issue 14, 2267-2270 (2006).
DOI: 10.1002/anie.200504529

Photopolymerizable Collagen Mimetic Peptide Conjugated PEG Hydrogel
H. Janice Lee, Jin-Soo Lee, Thanissara Chansakul, Christopher Yu, Jennifer H. Elisseeff, and Seungju M. Yu. Biomaterials Vol. 27, Issue 30, 5268-5276 (2006).
DOI: 10.1016/j.biomaterials.2006.06.001

Facile Modification of Collagen Directed by Collagen Mimetic Peptides
Allen Y. Wang, Xiao Mo, Christopher S. Chen, and Seungju M. Yu. Journal of American Chemical Society Vol. 127, Issue 12, 4130-4131 (2005).
DOI: 10.1021/ja0431915

See more publications »

Teaching

510.316 Biomaterials I

This course offers an overview of principles and properties of biomedical materials.  Topics include properties of materials used in medicine, synthesis and properties of polymeric materials, polymeric biomaterials, natural and recombinant biomaterials, biodegradable materials, hydrogels, stimuli-sensitive materials, and characterizations of biomaterials. (Fall 2008)

510.606 Chemical and Biological Properties of Materials (Graduate)

An introduction to the chemical and biological properties of organic and inorganic materials. Topics include an introduction to polymer science, polymer synthesis, chemical synthesis, and modification of inorganic materials, biomineralization, biosynthesis, and properties of natural materials (proteins, DNA, and polysaccharides), structure-property relationships in polymeric materials (synthetic polymers and structural proteins), and materials for biomedical applications. (Fall 2008)

Awards

• Presidential Earlier Career Award for Scientists and Engineers (PECASE), 2008
• NSF Career Award, 2007-2012
• NIH Post-Doctoral Fellowship, 1999 - 2001.
• University of Massachusetts Graduate Fellowship, 1993.
• Outstanding Academic Achievement Award, Korea University, 1988.