Michael S. Yu

Associate Professor, Materials Science and Engineering

Michael S. Yu at Materials Science and Engineering

office (410) 516-8935

lab (410) 516-2357

Institute for NanoBioTechnology

Yu Research Group Website

Maryland Hall 107

Research Interests

  • Synthesis and application of protein-based materials
  • Bio-inspired nanostructured materials
  • Biosynthesis of artificial proteins
  • Biomaterials for tissue engineering
  • Polymeric liquid crystals

CV/Bio

  • Ph.D. in Polymer Science and Engineering, University of Massachusetts at Amherst, 1998
  • M.S. in Organic Chemistry, Korea University, Seoul, Korea, 1993
  • B.S. in Chemistry, Korea University, Seoul, Korea, 1990

Classes

  • 510.619 Biopolymers Synthesis (Graduate) - In this course, we will review the current synthetic methods for preparing biopolymers of both synthetic and natural origin. The class will focus mainly on polypeptides and polysaccharides, but natural polyesters and polynucleotides (DNA and RNA) will be covered as well. Some of the main topics are; solid phase peptide synthesis, ring-opening polymerization for poly peptide synthesis, recombinant DNA and bacterial protein synthesis, bacterial production of biodegradable polyester, and chemical and biological engineering of polysaccharides. (Fall 2011)
  • 510.316 Biomaterials I - This course offers an overview of principles and properties of biomedical materials.  Topics include properties of materials used in medicine, synthesis and properties of polymeric materials, polymeric biomaterials, natural and recombinant biomaterials, biodegradable materials, hydrogels, stimuli-sensitive materials, and characterizations of biomaterials. (Fall 2008)
  • 510.606 Chemical and Biological Properties of Materials (Graduate) - An introduction to the chemical and biological properties of organic and inorganic materials. Topics include an introduction to polymer science, polymer synthesis, chemical synthesis, and modification of inorganic materials, biomineralization, biosynthesis, and properties of natural materials (proteins, DNA, and polysaccharides), structure-property relationships in polymeric materials (synthetic polymers and structural proteins), and materials for biomedical applications. (Fall 2008)

40Publications by Michael S. Yu

View on ResearcherID

  • Synthesis and Application of Gold Nanoparticles Functionalized with Collgen Mimetic Peptides

    XIAO,MO; YU,MICHAEL S.; 845, 845 AA 6.5.1. (2005)

  • Exploration of Collagen Mimetic Peptides

    YU,S.M.; WANG,A.Y.-L.; YUN,C.-S.; , (2003)

  • Piezoelectric devices: Squeezed virus produces electricity

    Yu, S. Michael; 7, 7 ()

  • Exploitation of collagen mimetic peptide as a collagen adhesive biopolymer for novel biomaterials de

    Yu, S. M.; Wang, Y. L.; Yun, C. S.; 1, 1 ()

  • Piezoelectric property of hot pressed electrospun poly(gamma-benzyl-alpha, L-glutamate) fibers

    Ren, Kailiang; Wilson, William L.; West, James E.; Zhang, Q. M.; Yu, S. Michael; 107, 107 ()

  • Syntheses and application of gold nanoparticles functionalized with collagen mimetic peptides

    Mo, X.; Yu, S. M.; 845, 845 ()

  • Biotemplate-directed synthesis and assembly of nanocrystals

    Mo, X.; Yu, S. M.; 226, 226 ()

  • Targeting collagen strands by photo-triggered triple-helix hybridization

    Li, Y; Foss, CA; Summerfield, DD; Doyle, JJ; Torok, CM; Dietz, HC; Pomper, MG; Yu, SM; 109, 109 ()

  • On-the-resin N-terminal modification of long synthetic peptides

    Stahl, Patrick J.; Cruz, Juan C.; Li, Yang; Yu, S. Michael; Hristova, Kalina; 424, 424 ()

  • Biotemplate directed 2-dimensional nanostructure assembly

    Yu, S. J. M.; Mo, M.; Krebs, M. P.; 735, 735 ()

  • Nanometer-Scale Smectic Ordering of Genetically Engineered Rod-Like Polymers

    YU,S.M.; SOTO,C.M.; TIRRELL,D.A.; 122, 122 ()

  • An Improved Tripod Amphiphile for Membrane Protein Solubilization

    YU,S.M.; MCQUADE,D.T.; QUINN,M.A.; HACKENBURGER,C.P.K.; POLANS,A.S.; KREBS,M.P.; GELLMAN,S.H.; IMPROVED,AN; AMPHIPHILE,TRIPOD; MEMBRANE,FOR; SOLUBILIZATION,PROTEIN; 9, 9 ()

  • Smectic Ordering in Solutions and Films of a Rod-Like Polymer Owing to Monodispersity of Chain Lengt

    YU,S.M.; CONTICELLO,V.P.; ZHANG,G.; KAYSER,C.; FOURNIER,M.J.; MASON,T.L.; TIRRELL,D.A.; 389, 389 ()

  • Non-covalent modification of collagen scaffolds

    Yu, M. S.; 230, 230 ()

  • Collagen mimetic peptides: progress towards functional applications

    Yu, S. Michael; Li, Yang; Kim, Daniel; 7, 7 ()

  • Thermal and structural properties of biologically derived monodisperse hairy-rod polymers

    Yu, S. J. M.; Tirrell, D. A.; 1, 1 ()

  • Immobilization of growth factors on collagen scaffolds mediated by polyanionic collagen mimetic pept

    WANG,A.Y.; SHIRLEY,LEONG; YU-CHUAN,LIANG; CHIH,RU; HUANG,C.; CHEN,CHRISTOPHER S.; YU,SEUNGJU M.; 9, 9 ()

  • Spatio-temporal modification of collagen scaffolds mediated by triple helical propensity

    WANG,A.Y.; CATHERINE,A.; SHIRLEY,FOSS; LEONG,XIAO; MARTIN,MO; POMPER,G.; YU,SEUNGJU M.; 9, 9 ()

  • Facile modification of collagen directed by collagen mimetic peptides

    Wang, A. Y.; Mo, X.; Chen, C. S.; Yu, S. M.; 127, 127 ()

  • PEG-Based Hydrogels with Collagen Mimetic Peptide-Mediated and Tunable Physical Cross-Links

    Stahl, P. J.; Romano, N. H.; Wirtz, D.; Yu, S. M.; 11, 11 ()

  • Differential scanning calorimetric study of poly(3-hydroxyoctanoate) inclusions in bacterial cells

    Song, J. J.; Yoon, S. C.; Yu, S. M.; Lenz, R. W.; 23, 23 ()

  • Directed synthesis and assembly of nanoparticles using purple membrane

    Mo, X.; Krebs, M. P.; Yu, S. M.; 2, 2 ()

  • Nanoparticle-assisted visualization of binding interactions between collagen mimetic peptide and col

    Mo, X.; An, Y. J.; Yun, C. S.; Yu, S. M.; 45, 45 ()

  • Rigid amphiphiles for membrane protein manipulation

    McQuade, D. T.; Quinn, M. A.; Yu, S. M.; Polans, A. S.; Krebs, M. P.; Gellman, S. H.; 39, 39 ()

  • Internal Segregation of Side Chain Ordering in Hairy-Rod Polypeptide Monolayers at the Gas-Water Int

    MASAFUMI,F.; HEILMANN,R.K.; PERSHAN,P.S.; YU,S.M.; SOTO,C.M.; TIRRELL,D.A.; , ()

  • Template-Tethered Collagen Mimetic Peptides for Studying Heterotrimeric Triple-Helical Interactions

    Li, Y.; Mo, X. A.; Kim, D.; Yu, S. M.; 95, 95 ()

  • Enhanced Chondrogenesis of Mesenchymal Stem Cells in Collagen Mimetic Peptide-Mediated Microenvironm

    LEE,J.H.; YU,C.; CHANSAKUL,T.; HWANG,N.S.; VARGHESE,S.; YU,S.M.; ELISSEEFF,J.H.; 14, 14 ()

  • Polymerizable Collagen Mimetic Peptides for Hydrogel Composed of PEG and Collagen Mimetic Peptides

    LEE,H.J.; WANG,A.Y.; LEE,J.-S.; YU,MICHAEL S.; , ()

  • Photopolymerizable Collagen Mimetic Peptide Conjugated PEG Hydrogel

    LEE,H. JANICE; JIN-SOO,LEE; THANISSARA,CHANSAKUL; CHRISTOPHER,YU; ELISSEEFF,JENNIFER; YU,SEUNGJU M.; 27, 27 ()

  • A cellular model for the investigation of Fuchs’ Endothelial Corneal Dystrophy

    Kelliher, Clare; Chakravarti, Shukti; Vij, Neeraj; Mazur, Steve; Stahl, Patrick J.; Engler, Christoph; Matthaei, Mario; Yu, S. Michael; Jun, Albert S.; 93, 93 ()

  • NEW POLYARYLATES PREPARED FROM 2,5-BIS(ALPHA-PHENYLISOPROPYL)HYDROQUINONE, TEREPHTHALIC ACID AND ISO

    Jin, J. I.; Yu, S. J.; 16, 16 ()

  • Piezoelectric properties of polypeptide-PMMA molecular composites fabricated by contact charging

    Hwang, Yonghwan; Je, Yub; Farrar, Dawnielle; West, James E.; Yu, S. Michael; Moon, Wonkyu; 52, 52 ()

  • A Twisting Grain Boundary-like Twisted Smectic Phase in Monodisperse PBLG Produced by Recombinant DN

    HE,S.-J.; LEE,C.; GIDO,S.P.; YU,S.M.; TIRRELLA,D.A.; TWISTING,GRAIN; BOUNDARY-LIKE,TWISTED; SMECTIC,PHASE; MONODISPERSE,IN; PRODUCED,PBLG; RECOMBINANT,BY; TECHNIQUES,DNA; 31, 31 ()

  • Structure of PBLG Monolayers at the Gas-Water Interface

    FUKUTO,M.; HELIMANN,R.K.; PERSHAN,P.S.; YU,S.M.; GRIFFITHS,J.A.; TIRRELL,D.A.; 111, 111 ()

  • X-ray Measurements of Noncapillary Fluctuations from Liquid Surface

    FUKUTO,M.; HEILMANN,R.K.; PERSHAN,P.S.; GRIFFITHS,J.A.; YU,S.M.; TIRRELL,D.A.; 81, 81 ()

  • Confinement-induced order of tethered alkyl chains at the water/vapor interface

    Fukuto, M.; Heilmann, R. K.; Pershan, P. S.; Yu, S. M.; Soto, C. M.; Tirrell, D. A.; 66, 66 ()

  • New Materials with Piezoelectric Properties

    FARRAR,D.; YU,M.; WEST,J.E.; BUSCH-VISHNIAC,I.; BIERMANN,P.; ARVELO,J.I.; , ()

  • Fabrication of Polypeptide-Based Piezoelectric Composite Polymer Film

    FARRAR,D.; WEST,JAMES E.; BUSCH-VISHNIAC,ILENE J.; YU,SEUNGJU M.; 59, 59 ()

  • Permanent Polarity and Piezoelectricity of Electrospun alpha-Helical Poly(alpha-Amino Acid) Fibers

    Farrar, Dawnielle; Ren, Kailiang; Cheng, Derek; Kim, Sungjoo; Moon, Wonkyu; Wilson, William L.; West, James E.; Yu, S. Michael; 23, 23 ()

  • Matrix-Bound VEGF Mimetic Peptides: Design and Endothelial-Cell Activation in Collagen Scaffolds

    Chan, Tania R.; Stahl, Patrick J.; Yu, S. Michael; 21, 21 ()

Awards

  • Presidential Earlier Career Award for Scientists and Engineers (PECASE), 2008
  • NSF Career Award, 2007-2012
  • NIH Post-Doctoral Fellowship, 1999 - 2001.
  • University of Massachusetts Graduate Fellowship, 1993.
  • Outstanding Academic Achievement Award, Korea University, 1988.

Group Members