Kalina Hristova

Professor, Materials Science and Engineering

Kalina Hristova at Materials Science and Engineering

office (410) 516-8939

Institute for NanoBioTechnology

Research Group

Maryland Hall 102

Research Interests

  • Membrane biophysics
  • Biomolecular materials
  • Biosurface interactions
  • Self-assembly of biological amphiphiles
  • Protein-lipid interactions

46Publications by Kalina Hristova

View on ResearcherID

  • Antimicrobial Peptides: Successes, Challenges and Unanswered Questions

    Wimley, William C.; Hristova, Kalina; Journal of Membrane Biology, 239 27 (2011)

  • Spontaneous Membrane-Translocating Peptides by Orthogonal High-Throughput Screening

    Marks, Jessica R.; Placone, Jesse; Hristova, Kalina; Wimley, William C.; Journal of the American Chemical Society, 133 8995 (2011)

  • Analysis of HIV-1 fusion peptide inhibition by synthetic peptides from E1 protein of GB virus C

    Jesus Sanchez-Martin, Maria; Hristova, Kalina; Pujol, Montserrat; Gomara, Maria J.; Haro, Isabel; Asuncion Alsina, M.; Antonia Busquets, M.; Journal of Colloid and Interface Science, 360 124 (2011)

  • A Look at Arginine in Membranes

    Hristova, Kalina; Wimley, William C.; Journal of Membrane Biology, 239 49 (2011)

  • FGFR3 Heterodimerization in Achondroplasia, the Most Common Form of Human Dwarfism

    He, Lijuan; Shobnam, Nadia; Wimley, William C.; Hristova, Kalina; Journal of Biological Chemistry, 286 13272 (2011)

  • Specific inhibition of a pathogenic receptor tyrosine kinase by its transmembrane domain

    He, Lijuan; Shobnam, Nadia; Hristova, Kalina; Biochimica Et Biophysica Acta-Biomembranes, 1808 253 (2011)

  • High-Throughput Selection of Transmembrane Sequences That Enhance Receptor Tyrosine Kinase Activatio

    He, Lijuan; Hoffmann, Andrew R.; Serrano, Christopher; Hristova, Kalina; Wimley, William C.; Journal of Molecular Biology, 412 43 (2011)

  • The Physical Basis of FGFR3 Response to fgf1 and fgf2

    Chen, Fenghao; Hristova, Kalina; Biochemistry, 50 8576 (2011)

  • The A391E mutation enhances FGFR3 activation in the absence of ligand

    Chen, Fenghao; Degnin, Catherine; Laederich, Melanie; Horton, William A.; Hristova, Kalina; Biochimica Et Biophysica Acta-Biomembranes, 1808 2045 (2011)

  • Assembly of the M2 Tetramer Is Strongly Modulated by Lipid Chain Length

    Schick, S; Chen, LR; Li, E; Lin, J; Koper, I; Hristova, K; Biophysical Journal, 99 1810 (2010)

  • Physical Basis behind Achondroplasia, the Most Common Form of Human Dwarfism

    He, LJ; Horton, W; Hristova, K; Journal of Biological Chemistry, 285 30103 (2010)

  • The Extracellular Domain of Fibroblast Growth Factor Receptor 3 Inhibits Ligand-Independent Dimeriza

    Chen, LR; Placone, J; Novicky, L; Hristova, K; Science Signaling, 3 (2010)

  • Measuring the Energetics of Membrane Protein Dimerization in Mammalian Membranes

    Chen, LR; Novicky, L; Merzlyakov, M; Hristov, T; Hristova, K; Journal of the American Chemical Society, 132 3628 (2010)

  • Polar residues in transmembrane helices can decrease electrophoretic mobility in polyacrylamide gels

    WALKENHORST, WF; MERZLYAKOV, M; HRISTOVA, K; WIMLEY, WC; BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1788 1321 (2009)

  • Hill Coefficient Analysis of Transmembrane Helix Dimerization

    SOONG, R; MERZLYAKOV, M; HRISTOVA, K; JOURNAL OF MEMBRANE BIOLOGY, 230 49 (2009)

  • MPEx: A tool for exploring membrane proteins

    SNIDER, C; JAYASINGHE, S; HRISTOVA, K; WHITE, SH; PROTEIN SCIENCE, 18 2624 (2009)

  • Increased expression of the integral membrane protein ErbB2 in Chinese hamster ovary cells expressin

    O'CONNOR, S; LI, EW; MAJORS, BS; HE, LJ; PLACONE, J; BAYCIN, D; BETENBAUGH, MJ; HRISTOVA, K; PROTEIN EXPRESSION AND PURIFICATION, 67 41 (2009)

  • Viewing the bilayer hydrocarbon core using neutron diffraction

    HAN,X.; HRISTOVA,K.; Journal of Membrane Biology, (2009)

  • Energetics of ErbB1 Transmembrane Domain Dimerization in Lipid Bilayers

    CHEN, LR; MERZLYAKOV, M; COHEN, T; SHAI, Y; HRISTOVA, K; BIOPHYSICAL JOURNAL, 96 4622 (2009)

  • A simple

    POSOKHOV,Y.O.; MERZYAKOV,M.; HRISTOVA,K.; LADOKHIN,A.S.; Analytical Biochemistry, 380 134 (2008)

  • A surface supported bilayer platform for studies of lateral association of proteins in membranes

    MERZYAKOV,M.; LI,E.; HRISTOVA,K.; Biointerphases, 80 (2008)

  • FRET measurements of transmembrane helix dimerization

    MERZLYAKOV,M.; HRISTOVA,K.; Methods in Enzymology, 450 107 (2008)

  • Quantitative measurements of protein interactions in a crowded cellular environment

    LI,E.; PLACONE,J.; MERZYAKOV,M.; HRISTOVA,K.; Analytical Chemistry, 80 5976 (2008)

  • Pathogenic activation of receptor tyrosine kinases in cellular membranes

    HE,L.; HRISTOVA,K.; Journal of Molecular Biology, 384 1130 (2008)

  • Protein Folding In Membranes: Insights from Neutron Diffraction Studies of a Membrane beta-Sheet Ol

    HAN,X.; HRISTOVA,K.; WIMLEY,W.C.; Biophysical Journal, 94 492 (2008)

  • EFFECT OF PATHOGENIC CYSTEINE MUTATIONS ON FGFR3 TRANSMEMBRANE DOMAIN DIMERIZATION IN DETERGENTS AND

    MIN; ,YOU; SPANGLER,JAMIE; EDWIN; ,LI; XUE; ,HAN; PIJUSH; ,GHOSH; HRISTOVA,KALINA; Biochemistry, 46 11039 (2007)

  • Studies of receptor tyrosine kinase transmembrane domain dimerization: The EmEx-FRET method

    MERZLYAKOV,M.; CHEN,L.; HRISTOVA,K.; Journal of Membrane Biology, 215 93 (2007)

  • Bias dependent admittance in hybrid bilayer membranes

    NIKOLOV,V.; RADISIC,A.; HRISTOVA,K.; SEARSON,P.C.; Langmuir, 22 7156 (2006)

  • Transmembrane helix heterodimerization in lipid bilayers: probing the energetics behind autosomal do

    MERZLYAKOV,M.; YOU,MIN; LI,E.; HRISTOVA,K.; Journal of Molecular Biology, 358 1 (2006)

  • Spectral FRET detection of protein interactions in surface supported bilayers

    MERZLYAKOV,M.; RACHEL CASAS,E.LI; HRISTOVA,K.; Langmuir, 22 6986 (2006)

  • Directed Assembly of surface-supported bilayers with transmembrane helices.

    MERZLYAKOV,M.; LI,E.; HRISTOVA,K.; Langmuir, 22 1247 (2006)

  • Surface-supported bilayers with transmembrane helices: the role of the polymer cushion revisited

    MERZLYAKOV,M.; LI,E.; GITSOV,I.; HRISTOVA,K.; Langmuir, 22 10145 (2006)

  • The achondroplasia mutation does not alter the dimerization energetics of FGFR3 transmembrane domain

    M.YOU,E.LI; HRISTOVA,K.; Biochemistry, 5551 (2006)

  • FGFR3 Dimer stabilization due to a single amino acid pathogenic mutation.

    LI,E.; YOU,M.; HRISTOVA,K.; Journal of Molecular Biology, 356 600 (2006)

  • Role of Receptor Tyrosine Kinase Transmembrane Domains in Cell Signaling and Human Pathologies

    LI,E.; HRISTOVA,K.; Biochemistry, 45 6241 (2006)

  • Book Review:

    HRISTOVA,K.; ChemBioChem, 7 1279 (2006)

  • Neutron diffraction studies of fluid bilayers with transmembrane proteins: Structural consequences o

    HAN,X.; HRISTOVA,K.; Biophysical Journal, 91 3736 (2006)

  • FRET in liposomes: Measurements of transmembrane helix dimerization in the native bilayer environmen

    YOU,M; LI,E.; WIMLEY,W.C.; HRISTOVA,K.; Analytical Biochemistry, 340 154 (2005)

  • SDS-PAGE and FRET suggest weak interactions between FGFR3 TM domains in the absence of extracellular

    LI,E; YOU,M.; HRISTOVA,K.; Biochemisty, 44 352 (2005)

  • Synthesis and initial characterization of FGFR3 transmembrane domain: Consequences of sequence modif

    IWAMOTO; ,TAKEO; YOU; ,MIN; EDWIN,LI; SPANGLER; ,JAMIE; TOMICH; ,JOHN M; HRISTOVA,KALINA; BBA-Biomembranes, 1668 240 (2005)

  • An experiment-based algorithm for predicting the partitioning of unfolded peptides into phosphatidyl

    HRISTOVA,K.; WHITE,S.H.; Biochemistry, 44 12614 (2005)

  • Imaging FRET Measurements of Transmembrane Helix Interactions in Lipid Bilayers on a Solid Support

    LI,E; HRISTOVA,K.; Langmuir, 20 9053 (2004)

  • How membranes shape protein structure

    WHITE,S.H.; LADOKHIN,A.S.; JAYASINGHE,S.; HRISTOVA,K.; Journal of Biological Chemistry, 276 32395 (2001)

  • MPtopo: A database of membrane protein topology

    JAYASINGHE,S.; HRISTOVA,K.; WHITE,S.H.; Protein Science, 10 455 (2001)

  • Energetics, stability, and prediction of transmembrane helices

    JAYASINGHE,S.; HRISTOVA,K.; WHITE,S.H.; Journal of Molecular Biology, 321 927 (2001)

  • Melittin at the bilayer interface: Structure and lipid perturbations

    HRISTOVA,K.; DEMPSEY,C.E.; WHITE,S.H.; Biophysical Journal, 80 801 (2001)

Awards

  • The Margaret Oakley Dayhoff award from the Biophysical Society, 2007.

Group Members